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Use only as part of a comprehensive prevention strategy that includes safer sex practices, regular testing for HIV-1 and other STIs, and counseling on reducing sexual risk behaviors. If recent exposures are suspected or symptoms of acute HIV infection are present e. Counsel individuals to strictly adhere to their dosing schedule, as efficacy is strongly correlated with adherence. Some individuals, such as adolescents, may benefit from more frequent visits and counseling.

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Committee on Gynecologic Practice. Preexposure prophylaxis for the prevention of human immunodeficiency virus. Accessed June 14, Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.

Antiretroviral prophylaxis for HIV prevention in heterosexual men and women [supplementary appendix]. Lifetime risk of HIV diagnosis. HIV Surveillance Report, ; vol Accessed July 9, Anal sex and HIV risk.

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National Transgender Comfirt Survey: The only medication approved to significantly reduce the risk of sexually acquired HIV-1 in individuals at risk, in combination with safer sex practices. Emphasize the importance of counseling on adherence and comprehensive HIV risk reduction. PrEP pre-exposure prophylaxis and PEP post-exposure prophylaxis in combination with behavioral interventions that support engagement in care and adherence to treatment. TasP treatment as prevention in HIV-positive individuals.

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